Chromosome 10p duplication syndrome. 10p+ syndrome. Trisomy 10p.
Incidence
Very rare syndrome. Sporadic.
Clinical Characteristics
Duplication of the short arm of chromosome 10 with a variable phenotype depending on the size of the trisomic segment. Growth and mental retardation, craniofacial dysmorphism, and ocular, cardiovascular, skeletal, and other abnormalities are associated.
Precipitants
None
Provocation Tests
None
Diagnostic Procedures
Karyotype. Duplication of the short arm of chromosome 10.