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Chromosome 8q duplication syndrome. 8q+ syndrome. Trisomy 8q.

Incidence

Very rare syndrome. Sporadic.

Clinical Characteristics

Duplication of the long arm of chromosome 8. The most commonly associated abnormalities include low birth weight, mental deficiency, prominent forehead, flat occiput, hypertelorism, upslanting palpebral fissures, ear and nose deformities, thin upper lips, and skeletal defects. The phenotype varies in relation to the type of duplication.

Precipitants

None

Provocation Tests

None

Diagnostic Procedures

Karyotype. Duplication of the long arm of chromosome 8.

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