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Chromosome 3q deletion syndrome. 3q minus syndrome

Incidence

Rare syndrome.

Clinical Characteristics

Deletion of the long arm of chromosome 3 with a variable phenotype consisting mainly of microcephaly, unusual facial appearance, eye abnormalities, deformed ears, and delay in growth and development. Partial deletion of the long arm of chromosome 3 is also involved in the blepharophimosis-ptosis-epicanthus inversus syndrome.

Precipitants

None

Provocation Tests

None

Diagnostic Procedures

Karyotype. Deletion of the long arm of chromosome 3. Several deletions are included. Deletion 3q22.3 is associated with the blepharophimosis-ptosis-epicanthus inversus (BPES) syndrome.

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