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Chromosome 1q deletion syndrome. 1q minus syndrome.

Incidence

Some cases are associated with ring chromosomes.

Clinical Characteristics

Deletion of the long arm of chromosome 1 characterized by multiple anomalies and neurological signs, including psychomotor and developmental delay, hypotonia, seizures, characteristic facies, congenital heart diseases, osseous defects, and genital anomalies.

Precipitants

None

Provocation Tests

None

Diagnostic Procedures

Karyotype shows deletion of the long arm of chromosome 1.

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